Salbutamol 4 mg Tablets

Description Salbutamol 4 mg Tablets — Swiss Remedies Brand: Swiss Remedies Category: β2-Adrenergic Research Compound Content: 100 tablets × 4 mg (400 mg total) Price: €39 Manufactured in: Switzerland ???? Product Overview Salbutamol (USAN: albuterol) is a short-acting, selective β2-adrenergic receptor agonist used in laboratories as a reference bronchodilator and β2-selectivity probe. It relaxes airway smooth muscle via β2-receptor activation, cAMP elevation, and PKA-mediated reduction of intracellular calcium. Because of its well-defined pharmacology, salbutamol is a core comparator in respiratory and receptor-target studies. ✅ Key Research Highlights β2-agonist benchmark: Canonical reference for bronchodilation, cAMP signaling, β2-selectivity, and smooth-muscle physiology studies. Exercise physiology & anti-doping relevance: Controlled studies show no performance improvement in non-asthmatic athletes at inhaled doses up to 1600 μg/24 h (JSSM). Used extensively in anti-doping pharmacokinetics research. WADA compliance modeling: WADA permits only inhaled salbutamol ≤1600 μg/24 h; oral/systemic administration is prohibited. Urinary threshold: ~1000 ng/mL (S3 Beta-2 Agonists). ???? Suggested Laboratory Applications β2-receptor pharmacology assays Bronchodilator response and smooth-muscle relaxation studies cAMP/PKA signaling models Receptor selectivity and structure-activity analyses Anti-doping threshold and detection research ???? Technical Specifications Field Data Chemical Name Salbutamol (Albuterol) Chemical Formula (base) C13H21NO3 Molecular Weight (base) 239.31 g/mol CAS Numbers Base: 18559-94-9; Sulfate: 51022-70-9 Class / Target Short-acting β2-adrenergic receptor agonist (β2AR) Strength / Pack 4 mg per tablet × 100 tablets (400 mg total) Storage Store dry, cool, and protected from light; follow SDS Shelf-Life 36 months (per COA/label) ❄️ Mechanism of Action (Laboratory Context) Activation of β2-receptors (Gs-coupled) → stimulation of adenylyl cyclase → ↑ cAMP → PKA activation → reduced intracellular Ca2 & MLCK activity → smooth-muscle relaxation and bronchodilation. ⚠️ Documented Research Side Effects Tremor and fine-muscle activation Tachycardia and palpitations (β1 spillover at higher doses) Hypokalemia via β2-mediated potassium shift Lactic acidosis in high systemic exposures Hyperglycemia and metabolic shifts Rare hypersensitivity reactions reported in clinical labeling ???? Handling & Compliance For Research Use Only — not a medicine, supplement, or veterinary product. Buyer affirms qualified laboratory use and compliance with institutional SOPs and local regulations. Salbutamol is regulated under WADA S3 Beta-2 Agonists; systemic/oral use is prohibited without a TUE.